Lionel Messi, Luis Suarez and Neymar are set to lead Barcelona's attack for the crucial visit of Atletico Madrid on Wednesday night (21 September). The injured Samuel Umtiti is the most notorious absentee in the Catalans' 18-man squad to face Los Colchoneros, but Sergio Busquets and Lucas Digne return after being rested in the weekend 5-1 victory over Leganes. Luis Enrique ruled out third keeper Jordi Masip, Rafinha and the out-of-favour Aleix Vidal due to technical reasons.
Barcelona host Diego Simeone's side in their first major test of the campaign. They have won three of the four first La Liga games of the season and sit third in the table, three points behind Real Madrid and only one ahead of Atletico Madrid.
The Catalans have not lost with Atletico Madrid at the Nou Camp since 2006 but were knocked out by them in the Champions League semi-final last term, before Los Colchoneros were beating in the final by Real Madrid on penalties.
Luis Enrique's side are out for revenge in this La Liga encounter, which will be played after Real Madrid's clash with Villarreal at the Madrigal Stadium.
Barcelona arrive to the game following impressive victories over Celtic and Leganes, putting the unexpected home defeat in La Liga against Alaves behind them.
Messi, Suarez and Neymar found the net in both victories, with the Argentine scoring a hat-trick against Celtic before netting a brace against Leganes. The MSN trio will try to continue their good form against an Atletico side who had not conceded a single goal in their last four games, having drawn against Leganes before winning against Celta, PSV and Sporting Gijon.
Luis Enrique will also have a fresh Busquets back available after the midfielder was rested in the weekend victory over Leganes as part of Barcelona's rotation policy. The Spaniard is expected to form the midfield trident along Andres Iniesta and Ivan Rakitic.
Marc-Andre rer Stegen will be be in goal while the back-line is expected to be formed by Sergi Roberto, Gerard Pique, Javier Mascherano and Jordi Alba. Umititi was expected to play ahead of the Argentine in the heart of the defence but will miss the game after suffering a knee injury in the preparation.
Rafinha, Vidal and Masip will also miss the game due to technical reasons. The Brazilian started against Leganes but will watch the game from the stands to make space for Digne, who returned to the squad to provide competition for Alba at left-back after missing the weekend game. Meanwhile, Vidal has also been left out of the squad for the third game in a row amid speculations linking him with a move away from Barcelona, with the club reportedly interested in signing Arsenal's Hector Bellerin.