Liverpool defender Nathaniel Clyne has picked up a knee injury after his side's 2-1 victory over Swansea City. The right-back, who featured in all Premier League matches, played the entire match at the Liberty Stadium on 1 October.

According to the Liverpool Echo, the 25-year-old has been struggling with injuries over the past weeks. He has been playing through pain and has now suffered a knee injury after the Merseyside club's latest win.

Clyne's injury setback has seen him fail to make it to interim England manager Gareth Southgate's first squad. The Three Lions allowed Sam Allardyce to resign after a newspaper sting, where the 61-year-old advised undercover journalists posing as business on how to evade the Football Association's (FA) rules on player transfers.

The former Southampton star is not the only player to miss out on England's upcoming World Cup qualifiers against Malta and Slovenia. His club teammate Adam Lallana was also not included after that latter picked up a groin injury against the Welsh club.

Lallana was withdrawn from the starting lineup in the first half and was replaced by Daniel Sturridge. The latter along with Liverpool captain Jordan Henderson are the two players to have made it to Southgate's first England squad.

Clyne and Lallana will be joined by Dejan Lovren, as the latter was also withdrawn from the Croatia squad. The 27-year-old central defender picked up a groin injury in the final minutes of Liverpool's clash against Swansea.

The Reds will host their arch-rivals Manchester United after the international break on 17 October. Liverpool manager Jurgen Klopp confirmed injuries to Lallana and Lovren and he remains hopeful the duo could be fit to face Jose Mourinho's side.

Nathaniel Clyne
Nathaniel Clyne has started in all seven Premier League matches for Liverpool Getty

"Dejan was one of the last moments of the game. [It is a] groin [injury] for both, hopefully not that serious," Klopp was quoted as saying by Liverpool's official website.

"Adam felt it, tried it again and it didn't work. In this moment they have no chance for the national teams. But hopefully 16 days should be enough to bring them back onto the pitch for the next game.

"Things like this happen – there was no sign of it in the week. The pitch was a little bit wet, of course, so things like this can happen. It's not too nice but nothing else," he added.