Son, 24, was included in the South Korea team competing for gold at Rio 2016, as one of the three overage players in the squad. Elimination at the hands of Honduras at the quarter-final stage however sent them home early, but it does present Mauricio Pochettino with the option of recalling the former Bayer Leverkusen forward for his next game.
Spurs confirmed Son's availability but the club will be without the injured Hugo Lloris and Mousa Dembele, who still has a three-match suspension to serve.
The north London side will be without their captain Lloris for four weeks after he suffered a hamstring injury in the season-opening draw with Everton.
The injury immediately rules Lloris out of Premier League games against Crystal Palace (20 August), Liverpool (27 August), Stoke City (10 September) and possibly Sunderland (18 September). The France international will also miss the club's first game back in the Champions League, which is scheduled to take place on 13 or 14 of September. Dutchman Michel Vorm is set to deputise.
"We trust in Michel and he is doing well. In the pre-season from day one he was the first option keeper and he played a lot of friendly games so he is ready to compete," Pochettino told reporters, BBC Sport report.
"He is a keeper with a lot of experience in the Premier League and in international football. There is no doubt about his quality.
"The good thing is that Lloris only has a minor injury and he will be with the team very soon."
Summer signing Vincent Janssen could also be handed a full debut. Last season, Harry Kane carried much of the goal-scoring burden as the only recognised centre forward in the Spurs squad. Janssen now offers an alternative and Pochettino is keeping his options open ahead of the visit of Crystal Palace on Saturday, suggesting he could rest Kane, who looked jaded against Everton, and hand the Netherlands international a full debut.
"Harry needs to be ready for every game and it is my decision whether he plays or not," Pochettino told The Times on Monday. "But I am open too. It is about performance. Maybe they can play together or maybe we can play Vincent or Harry."