From Kelly Osbourne to Demi Moore: 8 Stars Whose Dramatic Weight Loss Sparked Ozempic Talks in 2026

From red carpets to press tours, several high-profile stars appeared noticeably slimmer this award season, setting off debates around 'Ozempic face,' shifting beauty standards, and the pressure to stay camera-ready.

When Ariana Grande and Cynthia Erivo stepped out during the 2025 Wicked: For Good press tour, their visibly slimmer appearances drew intense scrutiny, with both stars addressing ongoing body criticism at the time. That moment set the tone.

By early 2026, as red carpets rolled out, a new wave of noticeably leaner celebrity looks — from Kelly Osbourne to Demi Moore — pushed the conversation into overdrive.

1. Kelly Osbourne

Kelly Osbourne's BRIT Awards appearance was one of the first big flashpoints.

She walked out in a black sequined mini dress, but most of the attention went elsewhere. Photos highlighting her slimmer frame and sharper features spread almost instantly, with side-by-side comparisons picking up traction.

Kelly, who is grieving her late father and rock legend Ozzy Osbourne, later responded, asking for understanding and pointing to a difficult period in her life, while rejecting assumptions about recent weight-loss methods.

2. Demi Moore

Meanwhile, Demi Moore's red carpet appearances didn't go unnoticed either.

At both the Actors Awards and the Oscars, her visibly defined collarbones and slimmer arms became a major talking point, especially in zoomed-in clips that circulated widely online.

The conversation only grew as outlets compared her look to recent years, turning her into one of the most discussed figures of the season.

3. Emma Stone

Emma Stone's return to the awards circuit also drew attention.

Her BAFTAs and Oscars looks, both more fitted and minimal, put her slimmer frame front and centre. Comparisons to her recent appearances quickly followed online.

However, Stone has stayed quiet about it.

4. Nicole Kidman

Nicole Kidman's custom silver gown at the Oscars highlighted her narrow frame and sculpted features.

Red carpet coverage pointed out her sharper facial structure and ultra-slim arms, with many linking her appearance to the broader trend seen throughout the season. Her look became one of the most dissected of the night.

5. Oprah Winfrey

Oprah Winfrey's weight loss has been a topic of discussion for some time, but it continued into her 2026 appearances.

Stepping out in tailored, form-fitting outfits, her slimmer frame was once again highlighted during awards-related events. However, Oprah is one of the celebrities who has in the past admitted to using Ozempic for weight management.

6. Mindy Kaling

Mindy Kaling's appearance at the Actors Awards was a quieter addition to the trend.

She wore a fitted look that showed a more defined silhouette, which didn't go unnoticed in red carpet coverage and online reactions.

7. Michelle Yeoh

During promotions for Wicked: For Good and subsequent appearances, Michelle Yeoh showcased a noticeably skinnier frame.

Her tailored outfits and plunging necklines emphasised the change, with before-and-after comparisons from her Everything Everywhere All at Once era circulating widely.

8. Natalia Dyer

Known for her naturally petite frame, Natalia Dyer still sparked conversation after recent appearances tied to Stranger Things 5. Her red carpet look from the show's premiere became a highlight, as the actress was captured with an even slimmer look.

Her name soon joined the growing list of stars fueling the 2026 debate.

Furthermore, the discussion that initially picked up around Ariana Grande and Cynthia Erivo hasn't really slowed it's just moved from press tours to red carpets.