Arsenal are currently 12 points adrift of leaders Chelsea.
Tottenham have won their last three games in the league.
Rooney last featured in United's 2-0 win over West Bromwich Albion on 17 December.
Henderson is likely to miss Liverpool's trip to Sunderland on 2 January.
Van Ginkel scored eight goals in 13 appearances in his first loan spell at PSV.
The final match of 2016 sees Jurgen Klopp beat Pep Guardiola at Anfield.
The Blues can extend lead at Premier League summit to nine points with record-equalling 13th straight win.
Ibrahimovic has scored 12 goals in the league this season.
Chelsea are looking to make it 13 wins on the bounce.
Brannagan was set to join Bolton Wanderers on loan in January.
Everton are reportedly interested in the player.
Oxlade-Chamberlain has 18 months left on his current deal.
The 24-year-old's agent recently revealed offers to leave the club.
The England international limped off with a knee injury in the win over Hull.
Reports suggest the north London club will return with an improved offer.
Sam Johnstone will be let go on a temporary deal.
The Brazil midfielder left Stamford Bridge for a reported £60m.
The 29-year-old fights for the first time since her 2015 defeat to Holly Holm.
Manchester United will host Middlesbrough, which will be the last fixture of 2016 for both clubs.
Marcus Rashford is finding game time hard to come by.
Liverpool and Man City are separated by one point on the Premier League table.
Franck Kessie has scored six league goals in 16 appearances in debut Serie A season.
Ronaldo has scored 22 goals for club and country this season.
Elneny has made 10 league appearances for Arsenal.
Everton manager Ronald Koeman is willing to let Barkley leave, if the price is right.
Alex Oxlade-Chamberlain will also return to full training on Saturday.
The 23-year-old has started just eight games in the Premier League this season.
The Boro boss will be reunited with Jose Mourinho at Old Trafford on Saturday.
Coutinho has missed Liverpool's last six games with an ankle injury.
The 21-year-old is wanted by elite Premier League clubs.