While Tottenham Hotspur are on a run of six straight wins as they aim to close the gap on the league leaders, Chelsea are yet to blink in their pursuit of the Premier League crown.
After Spurs thumped Watford in last Saturday's early kick-off, Chelsea held their nerve at Dean Court in the evening game that day, easing to a 3-1 win over Bournemouth to keep the gap at seven points.
Mauricio Pochettino and his side will be hoping United can had them a break and deny the Blues another win at Old Trafford to open up the title race again. But Conte's side will make the journey north with no real injury problems to contend with.
Speaking at a press conference on Friday, the Chelsea boss said he may have to check on "one or two players" before the match on Saturday but expects to be at full-strength.
"No concerns. One or two situations to check, but no injuries," Conte told reporters, football.london report. "The situations are good, but I think we have another day to make the best decision for the team. I want to wait to tell you if it is alright."
Chelsea have beaten United twice in their two meetings this season, thrashing Mourinho's men 4-0 in their league meeting at Stamford Bridge back in October before securing a narrow 1-0 win in the FA Cup quarter-final last month.
United will be playing their fourth game in 16 days on Sunday and while they came through Thursday's Europa League quarter-final meeting with Anderlecht unscathed, they will not have a full squad available to them.
Marcos Rojo and Eric Bailly have started every game in April at the heart of defence with Phil Jones and Chris Smalling both ruled out with long-term injuries.
Ashley Young also missed the last two matches after limping out of the goalless draw with Everton while Juan Mata is currently sidelined having undergone groin surgery.
Perhaps most worryingly is Mourinho's recent admission that Antonio Valencia is "having problems" that prevent him from playing every game.
The right-back missed games against Everton and Sunderland but returned to the starting XI on Thursday, playing the full 90 minutes.