Where to watch live
Kick-off is at 1.30pm BST. Live coverage of the match is available on Sky Sports 1 and Sky Sports 1 HD. Catch the highlights of the match on Match of the Day 2 on BBC One and BBC One HD at 10.30pm BST.
It is the first time that Jose Mourinho will manage United in the Premier League on Sunday after being appointed in May as a replacement to Louis van Gaal following the Red Devils' FA Cup triumph.
The win over Crystal Palace in May helped them seal a berth in the 2016 Community Shield against Leicester City. Mourinho saw his side beat the Foxes 2-1, courtesy of two goals from Jesse Lingard and Zlatan Ibrahimovic.
Ibrahimovic is one of the four new additions at Old Trafford and he scored the winning header at Wembley to bag his first silverware as United player. Other signings included that of Paul Pogba as the France international rejoined his former club for a world-record transfer fee.
However, Pogba is suspended for the opening match against Bournemouth and it was unlikely that he would have featured, even if he was not suspended. He joins Chris Smalling as the two players to miss United's trip to The Goldsands Stadium.
Eddie Howe's side have added Jordan Ibe to their squad this summer as he arrived at Bournemouth from Liverpool. The winger is likely to start against United when they play their first match of the season in front of the home crowd.
Mourinho has admitted that it will not be easy for his side to beat Bournemouth in their own backyard. The former Chelsea manager will be looking to start the campaign on a brighter note with three points.
What managers say
Eddie Howe: "You can pick any one in United's team and they will be a threat, even the full-backs, [Antonio] Valencia and [Luke] Shaw. We are well aware of the test we have. Hopefully we give as good as we get."
Jose Mourinho: "They [Bournemouth] have the same manager and same players who came from the Championship together and didn't change the way they play. It is a good stable team and they will make a difficult match for us."
Betting Odds (betfair)
- AFC Bournemouth: 18/5
- Draw: 13/5
- Manchester United: 10/11
- Last five (all competitions): W D W D D
- Last result: Angers 0-1 AFC Bournemouth
- Last five (all competitions): W D W L W
- Last result: Leicester City 1-2 Manchester United
- Injured: Junior Stanislas, Tyrone Mings, Baily Cargill
- Doubtful: Emerson Hyndman
- Suspended: N/A
Possible XI: Boruc; Daniels, Cook, Francis, Smith; Surman, Arter; Gradel, King, Ibe; Wilson.
- Injured: Cameron Borthwick-Jackson
- Doubtful: N/A
- Suspended: Chris Smalling, Paul Pogba
Possible XI: De Gea; Valencia, Bailly, Blind, Shaw; Carrick, Fellaini; Lingard, Rooney, Martial, Ibrahimovic.