Arsenal manager Arsene Wenger says the club will begin a full scale enquiry into the injuries suffered by Mikel Arteta and Aaron Ramsey in the Premier League draw with Tottenham Hotpsur.
Arteta was replaced after just 28 minutes after picking up a calf injury and could miss the next three weeks while Ramsey went off with a hamstring problem in the early moments of the second half fna faces up to a month out of action.
Both players have been ruled out of Arsenal's Champions League group match against Galatasaray on Wednesday while Jack Wilshere will also miss the game after going off with a twisted ankle, leaving Wenger to bemoan the club's misfortune.
"We have to really look at what happened," he said.
"There's no logic as it's two players who were not involved in the week - no Arteta, not Ramsey - and they had quite a light week for them. We have to analyse what happened there. I don't understand."
Having missed the League Cup defeat to Southampton both Arteta and Ramsey were fresh for the weekend visit of Spurs but separate muscular problems means they join a growing Arsenal injury list.
Olivier Giroud and Mathieu Debuchy are out until 2015, Theo Walcott is not due to return from a knee injury until next month while Abou Diaby is not yet ready for a return in the Premier league.
The visit of Galastaray could see Wenger move youngster Calum Chambers into central midfield, forcing a defensive re-shuffle which might see Hector Bellerin recalled.
"He's been excellent in every position," Wenger said of Chambers. "And from the first to the last minute he has an unbelievable engine. He gets forward and puts crosses in as well
"I would consider playing Calum there [in midfield]. But I only have four defenders at the moment. I don't know what I'll do yet. Give me a bit of time, but [Mathieu] Flamini is the only option I see at the moment.
"It was a very harsh yellow card against Tottenham, and the one before at Villa was very harsh as well. It's a shame you can't appeal globally for the cards you get.
"I thought he played well and I will tell him to keep playing his game. The fact that he's keen and committed maybe sometimes leads him to commit spectacular fouls."