Chelsea duo Eden Hazard and N'Golo Kante have both been nominated for the PFA Player of the Season award.
But with Chelsea widely expected to close in on the Premier League title, it is thought one of the two players integral to their superb season will scoop the prize.
Tottenham midfielder Dele Alli leads the race for the PFA Young Player of the Year. Kane and Lukaku have also been nominated for the award with Leroy Sane (Manchester City), Jordan Pickford (Sunderland) and Michael Keane (Burnley) also nominated.
The winners of the awards will be announced on 23 April.
Kante was nominated for the award last season during Leicester City's historic title triumph, losing out to teammate Riyhad Mahrez. The France international left the King Power Stadium during the summer transfer window to join Chelsea, where he has seamlessly carried over his title-winning form in the heart of midfield.
After a wretched 2015-16 campaign where his side finished the season 10th, Hazard has rediscovered the form that saw him win this award during the title-winning 2014-15 season, having scored 14 goals and laid on five assists this term.
Lukaku and Kane are expected to duke it out for the Premier League's golden boot, with the Everton striker currently four goals ahead of the England international with 23 goals. Despite Arsenal's turbulent season, Sanchez is just behind them with 18 goals.
Ibrahimovic arrived in England last summer at the age of 34 but instantly found the goal scoring touch that has followed him throughout his career. The former Sweden international has struck 17 goals in the league for Manchester United this season, 11 more than nearest rival Juan Mata.
Alli is perhaps the most notable omission from the main award. The 21-year-old is however on course to win the Young Player of the Year award for the second year running after another stunning campaign that has seen him score 16 times this season.
PFA award nominees:
Men's PFA player of the year award: Eden Hazard (Chelsea), Zlatan Ibrahimovic (Manchester United), Harry Kane (Tottenham Hotspur), N'Golo Kante (Chelsea), Romelu Lukaku (Everton), Alexis Sanchez (Arsenal).
Men's PFA young player of the year award: Dele Alli (Tottenham), Harry Kane (Tottenham), Michael Keane (Burnley), Romelu Lukaku (Everton), Jordan Pickford (Sunderland), Leroy Sane (Manchester City).
Women's PFA player of the year award: Lucy Bronze (Manchester City), Karen Carney (Chelsea), Jane Ross (Manchester City), Jill Scott (Manchester City), Caroline Weir (Liverpool), Ellen White (Birmingham City).
Women's PFA young player of the year award: Millie Bright (Chelsea), Jess Carter (Birmingham City), Nikita Parris (Manchester City), Georgia Stanway (Manchester City, Keira Walsh (Manchester City), Caroline Weir (Liverpool).