Premier League champions Leicester City were held to a goalless draw against Arsenal with referee Mark Clattenburg becoming the centre of controversy after turning down a late penalty for the hosts.
Ahmed Musa was denied a spot kick in the final five minutes of the contest after he was clipped by Gunners' full-back Hector Bellerin with Clattenburg placed just yards away.
Francis Coquelin was also lucky to avoid being shown a second yellow card after bringing down Leandro Ulloa.
Claudio Ranieri's side also saw a penalty appeal turned down in the first-half when Danny Drinkwater went down under the challenge of Laurent Koscielny.
Elsewhere, newly promoted Burnley shocked Liverpool at Turf Moor. First-half goals from Sam Vokes and Andre Gray saw the Clarets take all three points after some distastrous defending from Jurgen Klopp's side. Nathaniel Clyne gave the ball away for the game's opener with new signing Steven Defour allowed to charge forward unchallenged to set up Gray's goal.
After putting five past Steaua Bucharest in their Champions League qualifier on Tuesday, Manchester City were in fine form again as they put four back Stoke City at the Britannia Stadium. Sergio Aguero scored his fourth and fifth goals of the week before substitute Nolito netted his own brace after Bojan pulled one back for the hosts from the penalty spot.
Hull City sit third in the Premier League table after beating Swansea City at the Liberty Stadium. Goals from Shaun Maloney and an own goal from Abel Hernandez sealed the victory for Mike Phelan's side.
Chelsea recovered from falling a goal behind to make it two wins from two after victory over Watford. Etienne Capoue scored his second goal of the season before Michy Batshuayi scored his first goal for the Blues to level the contest. With three minutes of the match remaining, Diego Costa latched onto a fine ball from Cesc Fabregas before slotting under Heurelho Gomes to seal the win.
Victor Wanyama scored a late winner for Tottenham Hotspur as they saw off Crystal Palace, sealing his side's first win of the season, while goals from Kevin Mirallas and Gareth Barry saw Everton come from behind to beat West Brom.