Full time: Arsenal 1-0 Southampton

Full time: Chelsea 3-0 Tottenham Hotspur

Full time: Everton 1-1 Hull City

Full time: Sunderland 1-4 Manchester City

Sergio Aguero
Getty Images

21:40: Full time in each of our four 7:45pm kick offs and we've had it all on this Wednesday night.

Arsenal left it late but are again in debt to Alexis Sanchez who scored with two minutes left to overcome a brave Southampton, who ended the game with 10-men after Toby Alderweireld's injury.

No such worries for Chelsea and Manchester City, who via Didier Drogba and Sergio Aguero individual display continue their grip on the Premier League's top two.

Elsewhere, Everton lose another half time lead as Sone Aluko's second half leveller for Hull grabs a much-needed point for Steve Bruce's side.

Well that is all we have time for on this Premier League live blog. We'll be back with live coverage of the weekend games but until then goodbye.

Full time: Everton 1-1 Hull City

Full time: Arsenal 1-0 Southampton

Full time: Chelsea 3-0 Tottenham Hotspur

Full time: Sunderland 1-4 Manchester City

21:33: Fraser Forster saves Southampton again after clawing away Giroud's header but the Gunners have their goal with two minutes left as Ramsey's cross is turned into a virtually open net by Sanchez. Hard on 10-man Saints.

Goal: Arsenal 1-0 Southampton (Alexis Sanchez)

21:30: Toby Alderweireld off with a hamstring injury and with Saints having used all three of their three substitutions they have to play the remaining five minutes plus added time with 10 men.

21:24: What have Arsenal got left? They're huffing and puffing at The Emirates without really making much progress while Southampton look very solid. Doing more justice to their decent start to the season than they did against Manchester City. Shane Long goes off and is replaced by Mayuka.

21:17: Too easy for Chelsea who grab a third though substitute Remy as he holds off Vertonghen to tuck beyond Lloris. In the north east, City have a fourth through the brilliant Aguero, who beats Vergini to the ball before scoring in off the post.

Goal: Chelsea 3-0 Tottenham Hotspur (Loic Remy)

Goal: Sunderland 1-4 Manchester City (Sergio Aguero)

21:13: Better from Arsenal who are knocking on the door at last. Sanchez plays a cross-field pass towards Giroud and Forster beats out the effort. Now Giroud and Danny Welbeck combine and Forster pulls off a terrific save to deny him.

21:10: Loic Remy replaces Didier Drogba at Stamford Bridge. Chelsea on auto-pilot.

21:09: Alex Oxlade-Chamberlain off and Olivier Giroud on with 25 minutes remaining at The Emirates. Fair to say the hosts' supporters are not happy with the change despite calling for the introduction of the French striker.

21:06: Danny Welbeck cuts inside from the right, turns and plays a blind pass to his left where there isn't a single Arsenal player and Southampton clear. Near realms of ineptitude from the Gunners this.

Goal: Everton 1-1 Hull City (Sone Aluko)

21:01: Two changes for Tottenham as Chadli and Paulinho come on for Lennon and Mason. Not shown much in this second half have Spurs.

20:59: Manchester City's four straight defeats at the Stadium of Light looks like coming to an end as Pablo Zabaleta gets a rare third goal as he latches onto Nasri's through pass and chips Pantilimon.

Goal: Latest: Sunderland 1-3 Manchester City (Pablo Zabaleta)

20:54: Two chances for Southampton. Pelle first has a volley blocked before a break from an Arsenal corner sees Long lash a shot over the bar with Pelle in a better position. Bad miss.

20:52: Interesting news from Stamford Bridge where Gary Cahill has been replaced by Kurt Zouma. Remember, Cahill was involved in a heavy collision with Jan Vertoghen in the first half. Are Chelsea getting it wrong regarding head injuries again?

20:48: Second halfs under way in the Premier League. More goals please.

20:37: Half time out each of our four Premier League games and here is a round-up of what we have seen so far.

It has been business as usual for Chelsea who lead by two after Eden Hazard and Didier Drogba benefited from Hugo Lloris errors. Everton are also ahead after their Belgian duo Kevin Mirallas and Romelu Lukaku combined to open the scoring.

Manchester City have turned things around to lead Sunderland. Connor Wickham has the hosts ahead but Sergio Ageruo continue his impressive form by scoring the first and making the second for Stevan Jovetic.

Not going according to plan for Arsenal however, who are being held by Southampton after a tight and tense first half in north London.

Half time: Sunderland 1-2 Manchester City

Half time: Arsenal 0-0 Southampton

Half time: Chelsea 2-0 Tottenham Hotspur

Half time: Everton 1-0 Hull City

21:31: Cazorla's free-kick and Welbeck's glancing header produces a fine reaction save from Forster. Arsenal kept out in stoppage time at the end of the half.

20:30: Southampton very much in this game at The Emirates and they almost take the lead again through Pelle, who shoots from range and sees Martinez make an easy save. Half-time approaching across the country.

20:26: The champions are in front for the first time at the Stadium of Light. Yaya Toure fires a ball into Aguero who turns and cross for Jovetic and the Montenegren stabs home. City leads and deservedly so.

Goal: Sunderland 1-2 Manchester City (Stevan Jovetic)

20:24: Not a good couple of minutes for Didier Drogba, who first sky s free-kick into the second tier before he totally miss-times a header from an Ivanovic cross and totally misses the target. An offside flag spares his blushes but barely.

20:20: The Toffees has been dominating at Goodison and they have a lead to reward that authority. Kevin Miralles gets past Michael Dawson and finds Lukaku on the run who smashes the ball beyond McGregor.

Goal: Everton 1-0 Hull City (Romelu Lukaku)

20:15: Jack Cork off and Yoshida on for Southampton. Shane Long moving around a little gingerly too. Problems for the Saints who have held their own in this opening half an hour.

20:11: Four goals in as many minutes in the Premier League. Chelsea are all but out of sight against Tottenham after two goals in double-quick time. The first as Hazard exchanges passes with Drogba before driving under Lloris before the French skipper's poor clearance leads to Drogba tucking away a second.

Sunderland put themselves a goal ahead through Connor Wickham, who scored at the Etihad Stadium last season you will remember, before that man Sergio Aguero tucks away his 13th league goal of the season.

Goal: Chelsea 2-0 Tottenham Hotspur (Didier Drogba)

Goal: Sunderland 1-1 Manchester City (Sergio Aguero)

Goal: Sunderland 1-0 Manchester City (Connor Wickham)

Goal: Chelsea 1-0 Tottenham Hotspur (Eden Hazard)

20:03: First shot in anger from Chelsea. Nice interplay on the edge of the Spurs box between Hazard and Fabregas, before the latter shoots tamely at Hugo Lloris. The Premier League leaders not had it all their own way in the opening 18 minutes.

20:00: Southampton have begun well at The Emirates and they should be ahead. Pelle exchanges passes with Davis, who heads the ball towards the Italian striker, but he blazes over from seven yards. Big opportunity

19:57: Two chances, but no goals for Harry Kane. The England Under-212 international pick-pockets Gary Cahill wide on the right and drives into the area before shooting across Thibaut Courtois but wide of goal.

19:55: Chance for the other north London side in action tonight, Arsenal, as Santi Cazorla feeds Danny Welbeck but the England forward's curled shot soars wide of Fraser Forster's goal.

19:53: Harry Kane almost has Tottenham ahead at Stamford Bridge. Lennon crosses first time from the right and Kane beats Terry to the jump and rattles the crossbar with his header. Spurs have started well and probably should be ahead.

19:51: Dangerous free-kick for Spurs on the left of the Chelsea area after Ivanovic fouls Kane. The balls goes through the back of the penalty area where Chiriches crosses for Vertonghen, who heads goalwards but over the bar. Gary Cahill has remained down after the clash and is receiving treatment. Doesn't look great for the England defender but he is sitting up.

19:48: First observation from The Emirates, where Andre Marriner officiates Arsenal for the first time since sending off Kieran Gibbs by mistake against Chelsea, there are a few empty seats behind the goal the hosts are attacking in the first half.

19:45: Here we go, we're under way in our four evening kick-offs in the Premier League, but not before a minute's applause in tribute to the Australian cricketer Phil Hughes at Stamford Bridge. Nice touch.

19:40: So we're approaching kick-off in our four 7:45pm kick-offs. We'll have updates from all the games as the goals as they go in with particular focus on Arsenal v Southampton and Chelsea v Tottenham Hotspur.

19:36: Will Manchester City be able to break their hoodoo at Sunderland tonight? The Black Cats have won the last four encounters at home 1-0, with everyone from Ji-dong Won to Adam Johnson providing the winning goals. Who will be the hero tonight or can City turn around that recent record?

19:31: Am reliably informed that it is rather chilly at each of our four Premier League grounds tonight, so just as well I am cooped up in an office across all of the matches tonight. Some tasty games in store where Southampton look to provide another surprise and continue Arsenal's problems while Spurs go in search of a first win at Stamford Bridge for 24 years.

19:22: Bits and pieces of team news from across the country tonight. Arsenal are without Olivier Giroud but are able to call upon Nacho Monreal despite fears over an injury. Southampton recall Shane Long in attack for the trip to The Emirates.

Chelsea and Tottenham made one change apiece as Didier Drogba replaces the suspended Diego Costa and Roberto Soldado is replaced by Erik Lamela.

Everton bring in Leon Osman for Samuel Eto'o from the loss at Spurs while Hull have made four alterations with Curtis Davies left out. Nikica Jelavic leading a one-man attack against his former club at Goodison Park.

Finally, at the Stadium of Light Dedryck Boyata comes in for injured Manchester City captain Vincent Kompany alongside Martin Demichelis. Stevan Jovetic partners Sergio Aguero up front. Sebastian Costes makes his first Sunderland start for the hosts.

19:13: Team news:

Arsenal v Southampton

Arsenal: Martinez, Chambers, Mertesacker, Koscielny, Monreal, Flamini, Ramsey, Cazorla, Chamberlain, Alexis, Welbeck

Southampton: Forster, Clyne, Fonte, Alderweireld, Bertrand, Wanyama, Cork, S. Davis, Tadić, Long, Pellè

Chelsea v Tottenham Hotspur

Chelsea: Courtois; Ivanovic, Cahill, Terry (c), Azpilicueta; Matic, Fabregas; Willian, Oscar, Hazard; Drogba.

Tottenham Hotspur: Lloris; Chiriches, Fazio, Vertonghen, Davies; Bentaleb, Mason; Lennon, Eriksen, Lamela; Kane.

Everton v Hull City

Everton: Howard, Coleman, Baines, Jagielka, Distin, Besic, Barry, Mirallas, Barkley, Osman, Lukaku

Hull City: McGregor, Rosenior, Chester, Meyer, Huddlestone, Livermore, Diame, Jelavic, Dawson, Elmohamady, Quinn

Sunderland v Manchester City

Sunderland:Pantilimon, Vergini, Reveillere, O'Shea (c), Coates, Cattermole, Larsson, Rodwell, Buckley, Wickham, Fletcher.

Manchester City: Hart, Zabaleta, Boyata, Demichelis, Clichy, Fernandinho, Toure, Nasri, Navas, Jovetic, Aguero

19:00: Is the tide starting to turn against Arsene Wenger? Victory over West Bromwich Albion was overshadowed by an unmissable banner calling for the French boss to leave the club. Was this a rare lapse from Gunners fans or the start of a rebellion against Wenger? Tonight's visit of Southampton, who beat them in the League Cup earlier this season, may give us clues of the growing feeling of discontent in north London.

Elsewhere, the Premier league's top two are in action as Manchester City travel to Sunderland - who kept out Jose Mourinho's men over the weekend - while Chelsea host Tottenham Hotspur as Mauricio Pochettino's side chase a first league win at Stamford Bridge since 1990. Everton v Hull City is our other offering on this bonus mid-week Premier League feast. Those Christmas lists can wait.