The 23-year-old German international and his compatriot played for a full 90 minutes in the Reds' 3-1 victory over Everton in the Merseyside derby on 1 April. The former Borussia Dortmund manager confirmed Can came of the match with a "full body bruise", while the centre-back is struggling with a back problem.
"Emre has kind of a full body bruise. Everywhere. We left him out on Monday because he had back pain, knee pain. Nothing serious, thank God. Really, he has knocks everywhere. I hope he will be fit," Klopp said, as quoted by the Liverpool Echo.
On Matip, the German boss explained: "Joel had a little bit of a back problem or two. He saw the doc before training so we will see. He should be okay."
Liverpool are already struggling with injuries as Sadio Mane joined Jordan Henderson and Adam Lallana at the club's treatment room. The Senegalese international suffered a knee injury in his side's derby victory over Everton and Klopp admitted the former Southampton star could miss the remainder of the season.
The Reds captain last featured in his side's 2-0 victory over Tottenham Hotspur on 11 February, while Lallana picked up a thigh injury while on international duty with England. Should Can fail to make himself available for the Bournemouth clash, Klopp will be left with Georginio Wijnaldum and Lucas Leiva as the two experienced midfielders in the squad.
However, the Liverpool manager stressed that he focussing on how to help his side seal three points against Bournemouth to strengthen their chances of qualifying for next season's Champions League.
"We don't think about what we miss, we think about what we can do to win this football game," Klopp noted.
"I can't remember the last time all the players were available and decisions were really difficult to make. It will be a similar line up, but not exactly the same. We have different options. We could bring experience or young boys."