A man in his 20s has died after a bus smashed into a car in east London.

London Ambulance Service was called to the scene of the crash in Essex Wharf, Clapton, at 2.20am where a car had collided with the N38 bus, which was travelling toward Whipps Cross.

Three other men who were in the car were also injured, one whose condition has been described as critical and the other two who are in a serious but stable condition.

The three men, all of whom were in their early-mid 20s, are being treated at an east London Hospital while the man who was fatally injured was pronounced dead at the scene.

Nine other people are thought to have sustained minor injuries.

London Ambulance Service said: "We were called at 2.17am today (4 June) to reports of a road traffic collision involving a bus and a car on Lea Bridge Road. We sent an advanced paramedic, two responders by car, 7 ambulance crews, our hazardous area response team, a medical team from London's Air Ambulance by car and four officers to the scene.

"Sadly one person was dead at the scene.

"Staff treated 13 patients – three men, reported to be in their 20s, one for an arm injury, the second for a head injury and the third for an arm and head injury. All three patients were taken as priorities to the Royal London Hospital."

"The fourth patient, a man reported to be in his 60s, was treated for back pain and taken as a priority to the Royal London Hospital. Another two patients, one with a knee injury, were taken to the Royal London Hospital.

"Seven patients with minor injuries were taken to Homerton Hospital."

Road closures are in place from Chatsworth Road with the junction of Lea Bridge Road to Orient Way at the junction with Lea Bridge Road.

No arrests have been made.