Newcastle United duo Massadio Haidara and Remy Cabella are both unavailable for the Premier League meeting with Manchester Unite on 4 March.
Cabella, 24, has missed the club's last two games with a knee injury and despite hopes of a return for the visit of Louis van Gaal's side, the Frenchman revealed via his Twitter account that he was still not fit.
But manager John Carver is hopeful of having the attacking midfielder back at his disposal for his side's clash with Everton on 15 March, along with Rolando Aarons and goalkeeper Rob Elliot.
"Remy Cabella will also be back for the start of next week so that is three very big positives for us," Carver said via Newcastle's official website.
"I'll look on the positive side that next week I have three very important players coming back to me who can make a difference."
French full-back Haidara will also miss the game at St James' Park after being stretchered off during the weekend victory over Aston Villa.
"Haidara, who we thought would be available, has got some slight fluid on his knee," Carver continued. "He's been for an injection this morning and so he's almost certainly not going to be available tomorrow night, but hopefully it settles down in time for Everton.
"Injuries are always a concern and sometimes it is the soft tissue injuries which are the bigger concern."
Manchester United, meanwhile, will remain without Robin van Persie, who is still unavailable after missing the 2-0 win over Sunderland with an ankle injury.
Michael Carrick, having recovered from a muscle rupture, was named on the bench for the victory over the Black Cats on 28 February but is not in contention to start having missed the club's previous six games.