Real Madrid only need to avoid defeat against Sporting Lisbon at the Estadio Jose Alvalade on 22 November to seal progress to the Champions League knockout stages.
Where to watch live
Kick-off is set for 7.45pm GMT. The game will be broadcast live on BT Sport ESPN.
Sporting Lisbon are five points behind Real Madrid in Champions League Group F and must beat the Spanish giants to have any chance of reaching the round of 16. Cristiano Ronaldo and Alvaro Morata scored late on for Real to condemn Sporting to a 2-1 defeat in the clubs' first meeting in the group stages back in September.
Jorge Jesus has no fresh injury concerns. Defender Bruno Paz misses out through suspension.
Ronaldo scored a hat-trick to help Real Madrid beat city rivals Atletico Madrid 3-0 at the Vicente Calderon on 19 November. The Portugal forward returns to the club where he began his career in 2002.
Casemiro (leg), Toni Kroos (foot), Morata and Pepe (both hamstring) are all out through injury for the visitors.
What managers say
Jorge Jesus: "We are up against the best team in the world; they are second to none. But we are confident in our abilities. We have a dream, and that is to play as we did in Madrid and win. We knew all about Madrid going into the first game, but they didn't know us that well. Here they won't be as surprised by our capabilities. They are strong when they have the ball. When they don't have the ball, they have weaknesses, like all teams, and we will try to capitalise."
Zinedine Zidane: "[In the first game] they didn't surprise us at all. We won with difficulty and tomorrow will be just as hard. In front of their passionate fans, Sporting will want to put us in trouble and the most important thing is that we must be ready as a team to face that threat. Winning as we did at the weekend [against Atletico Madrid] doesn't guarantee anything in the next game. If we go in strong, we know we can get something out of it. I won't be doing any calculations as to how each group might finish and nor will my players."
- Sporting Lisbon (all competitions): WWLDD
- Last result: Sporting Lisbon 5-1 Praiense (Portuguese Cup)
- Real Madrid (all competitions): WWDWW
- Last result: Atletico Madrid 0-3 Real Madrid
Betting odds (Betfair)
- Sporting Lisbon win: 9/2
- Draw: 29/10
- Real Madrid win: 8/13
Sporting Lisbon possible XI: Rui Patricio; Pereira, Coates, Semedo, Zeegelaar; Carvalho, Silva, Gelson, Ruiz, Cesar; Dost
Real Madrid possible XI: Navas; Carvajal, Varane, Ramos, Marcelo; Modric, Kovacic, Isco; Bale, Benzema, Ronaldo