- Dele Alli opens the scoring after 27 minutes.
- Deflected shot in the second half sees Alli double the lead.
- Christian Eriksen makes it three on the break.
- Cristiano Ronaldo pulls one back with 10 minutes left.
- Tottenham qualify for the last 16.
- Real Madrid lose group stage match for first time since 2012, ending 30-game unbeaten streak.
- Recap: Napoli 2-4 Manchester City, Liverpool 3-0 Maribor
Well that brings an end to our live coverage from Wembley. What a night for Spurs.
We'll have all the reaction from this game and across Europe throughout the night. We're back with live coverage of the Europa League tomorrow, but until next time it's goodnight.
It will take time to quantify that result, but for now it sees Tottenham reach the knock-out stage and join the likes of Bayern Munich, PSG and Manchester City in the second phase.
Real Madrid meanwhile are in turmoil and tonight's display was perhaps one which must question their commitment to Zinedine Zidane. We will watch his future with some interest.
Full time: Tottenham 3-1 Real Madrid
What a night for Mauricio Pochettino and Spurs. They beat Real Madrid for the first time and take their place in the Champions League last 16. Dele Alli comes of age with two goals in either half, with Christian Eriksen netting the third. Ronaldo grabbed a late consolation but in truth, Madrid barely deserved it. They were woeful and have now won just two of their last five.
Mousa Dembele takes a huge chunk out of Sergio Ramos and gets just a yellow card. A tad fortunate there perhaps; Ramos was fuming.
Ronaldo has another go and Lloris makes a fairly easy save. Tottenham conceding plenty of possession to Madrid but they're looking good to see out the win.
Ronaldo pulls one back for Real Madrid.
Real putting lots of pressure on Tottenham now as the hosts drop deep. It ends with Casemiro's deflected shot being saved by Lloris.
GOAL! Tottenham 3-1 Real Madrid (Cristiano Ronaldo)
A lifeline for Real? Spurs don't clear Marcelo's bouncing cross and it falls to Ronaldo who makes no mistake from eight yards. Could that spark a comeback?
Harry Kane off and Fernando Llorente off. Started slowly but has improved throughout, ending in laying on the third goal.
And that should have been the fourth. Dele Alli heads wide from six yards out. Bad miss in the grand scheme of things, but he's done the business tonight.
Goal-scorer Christian Eriksen leads the celebrations as Tottenham make it 3-0.
Asensio and Moyoral on for Real Madrid. Three down with 16 minutes to go, it's a case of damage limitation for the visitors.
Zinedine Zidane looks a beaten man.
Dele Alli smashes Tottenham into a two-goal lead.
GOAL! Tottenham 3-0 Real Madrid
The European champions cut apart. Dele Alli feeds Harry Kane, who lays the ball on perfectly for Eriksen who draws Casilla and calmly finds the net. Dreamland for Spurs.
A goal-mouth scramble to end all goal-mouth scrambles. No idea how Real Madrid have not pulled a goal back but between Ramos and Ronaldo the ball stays out.
GOAL! Tottenham 2-0 Real Madrid (Dele Alli)
Spurs double their lead and I would like to say they are playing their best, but they're not really close. Dele Alli surges forward, more of less un-tracked and his shot takes a wicket deflection off Sergio Ramos and wrong-foots Casilla. Where the Real defence was, I have no idea.
And now Michel Vorm is warming up. Bad news for Tottenham.
Better from Madrid and Marcelo escapes down the left and his driven cross towards Ronaldo is palmed away by Lloris and Dier clears the danger.
Hugo Lloris now in the wars as he goes down after a collision during a free-kick, with what looks like a groin problem. We'll see how that develops.
Better from Harry Kane, who looked half fit in the first half, as he pick-pockets Marcelo and cross towards Eriksen, but Nacho gets the ball clear.
Back under way Wembley. Indeed there are no changes.
Players on their way out as the second half approaches. Ben Davies is back after picking up a calf problem, so looks like no changes.