Crisis-hit Valencia must overturn a seven-goal deficit against Barcelona at the Mestalla on 10 February to reach the final of the Copa del Rey.
Where to watch
Kick-off is set for 8pm GMT. The game is not scheduled for live broadcast in the UK.
Valencia face a near-impossible task to qualify for the final of the Copa del Rey after they were dismantled 7-0 at the Nou Camp in last week's semi-final first leg. Head coach Gary Neville is under intense pressure after his team slipped to another league defeat at the weekend against Real Betis, extending the club's winless run in La Liga to 12 matches.
Forward Paco Alcacer has recovered from a knee injury and could feature against Barcelona, but centre-back Shkodran Mustafi is suspended after his red card at the Nou Camp. Barcelona marked Luis Enrique's 100th game as in charge of the club with a 2-0 win at Levante to maintain their three-point lead at the top of the league table. The Catalan giants are on a club record 28-match unbeaten run across all competitions.
Lionel Messi will not travel to Mestalla and will instead have his kidneys tested. Enrique is likely to rest several of his first-team players to keep them fresh for the weekend league encounter against Celta Vigo.
What managers say
Gary Neville: "I said before I came that I would be judged in five months. I have been judged in six weeks. It's clear that we are better than some of the teams we are playing against. Our last two league matches were not performances that deserved two defeats, but the reality is that they are two defeats and I am aware of the consequences when you don't get good results. What matters are results."
Luis Enrique: "I have the feeling that we did what we had to do to take the game. It is true that Levante could have gone in at half-time level on the scoreboard, or maybe even ahead, but I believe the result is fair. I have a marvellous feeling at the moment. These games can be difficult but I believe we gave a very complete performance."
- Valencia (all competitions): L L L W D
- Last result: Real Betis 1-0 Valencia
- Barcelona (all competitions): W W W W W
- Last result: Levante 0-2 Barcelona
Betting odds (888sport)
- Valencia win: 13/4
- Draw: 37/13
- Barcelona win: 4/5
Valencia possible XI: Ryan; Barragan, Santos, Abdennour, Gaya; Barbosa, Parejo, Gomes; Feghouli, Negredo, Mina.
Barcelona possible XI: Ter Stegen; Vidal, Vermaelen, Mathieu, Adriano; Turan, Busquets, Roberto; Munir, Suarez, Neymar.