Full-time: West Ham 1-0 Tottenham
- Man of the Match Manuel Lanzini powers home from close range in the 65th minute to all but end below-par Tottenham's Premier League title hopes and guarantee safety for West Ham
- Wins for leaders Chelsea against Middlesbrough and West Brom would see Antonio Conte's men wrap up the title before Spurs host Manchester United in their next match
- The Blues need six points from their final four games to seal success
- Victory for West Ham also a huge shot in the arm for underfire manager Slaven Bilic, whose future was said to hinge on his side's performances in their final two home outings
That is all from me, but keep your eyes peeled on IBTimes UK for post-match reaction from both Bilic and Pochettino. We will also be back on Sunday to bring you live coverage of Liverpool vs Southampton and Arsenal vs Manchester United.
Until next time, farewell.
In addition to ending their rivals' pursuit of a first top-flight title for 56 years, such a morale-boosting win secures another season of Premier League football for West Ham and provides a sizeable boost to Bilic's hopes of remaining in his current role beyond the end of the season.
Only a second win in 12 games, the Hammers are now unbeaten in their last five. Liverpool visit London Stadium next before the season ends with a potentially tricky trip to Burnley.
Barring an extraordinary turn of events, that is the title race now done and dusted. Chelsea, who have a very favourable run-in, need just six points from their last four games to guarantee success.
Wins on Monday and Friday at home to Middlesbrough and away at West Brom would see Antonio Conte's side wrap things up before Tottenham play again against Manchester United next weekend.
It's been a truly valiant late challenge from Spurs, but once again a poor result in a London derby has cost them. A 10th straight victory would have seen them narrow the gap to just a single point.
West Ham 1-0 Tottenham
Tottenham fail to create any late momentum and West Ham so nearly notch a second goal on the counter through substitute Fletcher.
The final whistle sounds.
Alli takes a tumble at the back post and his hopeful penalty appeals fall on deaf ears. Trippier is then booked for cynically halting a West Ham counter.
Spurs overload the West Ham box but Trippier's cross is overhit and sails out of play.
Fernandes comes on for goalscorer Lanzini, who is deservedly treated to a standing ovation.
Ashley Fletcher for the underwhelming Calleri is Bilic's second substitution. The fourth official's board goes up again and reveals five minutes of additional time.
Will there be a late twist in the tale?
Eriksen engineers a small pocket of space and proceeds to fire a shot just wide. Time is running out for Spurs.
Somewhere in West London, Antonio Conte will be grinning like the Cheshire Cat.
Noble skews a shot wide after positive work from Lanzini and a distracting dummy run from Cresswell.
A crucial intervention from Fonte prevents the ball running through for Eriksen in the six-yard box.
Ben Davies flattens Noble and Byram has to stop Kouyate and Alli squaring up to one another as tempers fray.
Bilic's first change sees Ayew make way for Robert Snodgrass.
Pochettino turns to his bench for the third and final time with 10 minutes remaining. Walker is replaced by Trippier.
What a save!
Vertonghen is inexplicably robbed of possession in his own penalty area by Calleri. The Deportivo Maldonado loanee then drifts beyond Alderweireld before unleashing a powerful shot that is excellently beaten away.
That really should have been 2-0.
Wanyama is the man to make way for Janssen, who plays a great one-two with Alli. The England midfielder tries to set up Kane, but his low pass arrives too late.
Byram tries to swap shirts with the elusive Son and receives a yellow card for his troubles. Tottenham are preparing to send on Vincent Janssen.
Pochettino responds to that setback by replacing Vertonghen with Moussa Dembele.
West Ham still in the ascendancy as Lanzini and Noble both shoot over the crossbar.
Deadlock broken after an untidy scramble in the Spurs box. Cresswell and Byram both provide crosses and Jan Vertonghen blocks Ayew's shot before Lanzini powers home from close range.
Is that the death knell for the title race and a goal that goes a long way to saving Bilic's job?
Goal: West Ham 1-0 Tottenham (Manuel Lanzini)
Just past the 60-minute mark and Adrian is called into action once more. The inconsistent Spaniard gets down low to push clear Son's strike after a smart decoy run from Walker occupies the attention of James Collins.
A fine pass from Walker frees up Son and the South Korean forward, who needs just one more goal to reach 20 for the season, quickly picks out Eriksen for a disappointingly tame shot that is easily gathered by Adrian.
Calleri puts too much power on a through ball for Ayew and that allows a grateful Lloris to make the clearance.
Preciously little space for Alli and Kane to work in that Tottenham final third. West Ham are doing a commendable job of keeping their main attacking threats at bay.