Arsenal manager Arsene Wenger has confirmed Aaron Ramsey and Danny Welbeck are doubts for the trip to Manchester United on 17 May, while Alex Oxlade-Chamberlain, Mathieu Debuchy and Mikel Arteta remain on the sidelines.
The Gunners, third in the league, are two points above Louis van Gaal's side after missing the chance to go level on points with Manchester City in second place following their 1-0 home defeat against Swansea on 11 May.
And having already beaten United earlier this season in the FA Cup quarter-final thanks to Danny Welbeck's goal, the north London side will try to get three points to consolidate finishing in the top three places in the Premier League in order to secure automatic qualification for next season's Champions League.
"Alex Oxlade-Chamberlain, Mathieu Debuchy and Mikel Arteta are not ready. Danny Welbeck has a little possibility to be fit," Wenger said to the club's website.
"I don't think we have any big injuries, maybe Welbeck will be available but at the moment he looks short. I don't know how long the others will be out for, it's difficult to say, but hopefully they will play again this season.
Meanwhile, the manager had an update on Ramsey's situation. He said: "Aaron Ramsey is not in training yet but he should be better tomorrow."
The Wales star has started the last seven Premier League games but recently claimed he would like to return to a central role after being forced to play on the right flank to make space for Mesut Ozil and Santi Cazorla in the middle of the park.
Wenger has deployed the same starting line-up in his last five Premier League games but, following the defeat against Swansea, he might make some changes at Old Trafford, especially considering the Gunners play Sunderland on 20 May.