Third-choice goalkeeper Emiliano Martinez was called into the first-team on Wednesday (5 April) but had a comfortable evening at the Emirates as the Gunners cruised to an easy 3-0 win over West Ham United. Cech is currently unavailable due to a calf injury with second choice shot stopper Ospina joining him on the sidelines after suffering a back injury in the 2-2 draw with Manchester City last Sunday.
Neither goalkeeper is available yet, meaning 24-year-old Martinez will be tasked with keeping out Sam Allardyce's side on Monday. Francis Coquelin meanwhile was absent from the Gunners' squad due to personal reasons on Wednesday but speaking at a press conference on Friday, Wenger confirmed the midfielder is available once again.
Laurent Koscielny, who limped off during the draw with Pep Guardiola's side, is another absentee, however. Wenger initially described the defender's Achilles injury as "serious," but told reporters that having seen the results of a scan, is confident the problem is not as bad as initially feared.
"Koscielny is shorter than expected, it not a ligament problem, a tendon problem," Wenger said.
In the absence of the France international with first-team captain Per Mertesacker left on the bench, Theo Walcott wore the armband on Wednesday night. Wenger is yet to to decide who will captain his side against Palace, however.
Arsenal's win over West Ham was their first in the Premier League since 11 February with Wenger paying tribute to his midfield pairing of Granit Xhaka and Mohamed Elneny for setting the tempo for that much needed victory, which keeps their hopes of a top four finish alive.
When asked about the midfield duo, Wenger said: "In the heart of the game it is not only the quality of the passing but the speed of our passing is needed for the way we want to play. We have quick strikers so it is important we feed them quickly, then the quality of decision making becomes important."