Paris Saint Germain could lose four members of their first team for their Champions League last 16 clash with Chelsea on Tuesday.
Yohan Cabaye, Marquinhos, Serge Aurier and Lucas Moura were all forced off as PSG surrendered a 2-0 lead to draw 2-2 with Caen on Saturday 14 February.
Former Newcastle United midfielder Cabaye was replaced by Adrien Rabiot after just 16 minutes when he suffered a muscular injury.
PSG ended the first half with a 2-0 lead lead thanks to goals from Zlatan Ibrahimovic and Ezequiel Lavezzi but centre half Marquinhos was unable to continue for the second due to a thigh injury.
Aurier, who provided the assist for his side's opener, was then stretchered off, before he was joined by Lucas who was also unable to continue, leaving PSG to play the remainder of the game with nine men.
Caen capitalised on a weakened PSG side and scored twice in the final two minutes to rob the champions of their chance to return to the summit of Ligue 1.
The spate of injuries will provide a welcomed boost for Jose Mourinho, whose side have had the weekend off due to their elimination from the FA Cup.
PSG boss Laurent Blanc had jokingly described his Chelsea counterpart as a 'genius' before his side's game, given the Blues' six-day rest before their Champions League clash.
"Chelsea? Jose Mourinho is a genius – he lost a cup game 4-2 and has given himself a week to prepare for our Champions League encounter," the PSG boss said.
"Imagine the tsunami it would be have been had we lost the same kind of game. We'd have said the Paris coach still didn't get it. That's how it is."