Where to watch
Kick-off is set for 2:05pm BST. There is no live coverage of the game but live commentary will be available on Sky Sports.
Manchester City will look to continue their bid for a top four finish after what has been a disappointing and ultimately trophyless first season for Pep Guardiola.
The last remaining goal of the season will be for the Citizens to finish as high as possible in the Premier League, currently in fourth place with 65 points with their top four status still not guaranteed for next season.
With five league games left in the season, Guardiola's men will need to win every game if they want to finish in the top three and avoid the Champions League qualifiers next season.
They will be without Claudio Bravo who suffered a potentially season-ending calf injury in the Manchester derby while there are still concerns over the fitness of David Silva and John Stones. However, Bacary Sagna is back after five weeks out.
As for Middlesbrough, it's now or never as with just four league games left in their campaign, Steve Agnew's side are currently 19th with 27 points, six points behind 17th place Hull City.
Their win over fellow relegation candidates Sunderland was a big boost but they will need the full support of their home fans more than ever against City at the Riverside Stadium.
The good news is that Gaston Ramirez is back after serving his suspension, however, Daniel Ayala is doubtful along with Victor Valdes and Grant Leadbitter.
What managers say
Steve Agnew: "It's another all or nothing match, but we're used to that in recent weeks. I've admired Pep [Guardiola] for many years. His team pass the ball and are very good in possession, with lots of movement. They have talent all over the pitch and can score goals for fun. But when we went to the Etihad we came away with a point, and in the FA Cup game we worked hard and had chances on the day," via BBC Sport.
Pep Guardiola: "What I've learned here is that the difficulty with the top and low teams are quite similar. Middlesbrough will be difficult, Palace, West Brom, Watford. Game by game, we'll try to win the points and ensure Champions League next season," via Manchester City.
Betting odds (Betfair)
- Middlesbrough to win: 12/1
- Draw: 5/1
- Manchester City to win: 3/10
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