Memphis Depay has managed just two goals in 20 Premier League appearances thus far this campaign.
The 40-year-old former captain has backed the United striker to star at the tournament this summer.
Wayne Rooney admitted disappointment after missing United's 3-0 win over Shrewsbury due to a knee injury.
Rooney is currently facing six weeks on the sidelines after suffering a knee injury during United's recent loss against Sunderland.
Wayne Rooney picked up a knee injury and is expected to be on the sidelines for up to two months.
James Wilson will remain on loan at Brighton and Hove Albion until the end of the season despite injury troubles a United.
Roy Hodgson can learn about other attacking combinations in the absence of England's record scorer.
Donald Love made his debut as a substitute during Manchester United's loss to Sunderland in the PL on 13 February.
Matteo Darmian and Cameron Borthwick-Jackson will also miss the game.
Louis van Gaal expected to explain absence of his captain in forthcoming press conference.
Wayne Rooney wants the Red Devils to concentrate on winning the Europa League.
The 78-year-old icon made 758 appearances for the Red Devils, scoring a record 249 goals.
The former England boss has predicted more big-name players will soon make the switch.
The 26-year-old striker has barely featured for the Reds under new manager Jurgen Klopp.
The 26-year-old defender says Marcos Rojo and Sergio Romero are the toughest Red Devils squad members.
Memphis Depay has struggled to adapt to the pace of the Premier League after impressing in the opening months.
The 26-year-old striker has barely featured for the Reds under new manager Jurgen Klopp.
Manchester United goalkeeper David de Gea has kept 13 clean sheets in 28 appearances thus far this campaign.
A host of big-name players have been linked with moves to Asia in recent months.
The 20-year-old Frenchman delivered another eye-catching performance against Stoke City.
Anthony Martial was named man of the match for a second game in a row after receiving the plaudits during their 3-1 win over Burnley in the FA Cup.
The 20-year-old Frenchman has relished training and playing alongside the record-breaking forward.