Polls predict Macron will beat Le Pen in the April first-round after a two-week surge in popularity.
Le Pen is an anti-woman candidate, despite her claims to the contrary.
Fillon received the interest free, undeclared personal loan in 2013 from business mogul Marc Ladreit de Lacharrière.
The pressure group SOS Autism has criticised the candidate's comments as "intolerable."
French president said the French elections will be a watershed moment for the whole of Europe.
Wife of François Fillon has been accused of taking fake parliamentary jobs
Embattled French centre-right contender refuses to stand down over allegations of illegal payments to wife and children.
The presidential hopeful, who is leading current polls, has dismissed the vote as 'political interference'.
Macron has announced a six-tier plan to deliver his vision for France.
French presidential candidate speaks out over 'odious' homosexual accusations.
Fillon had been seen as the most likely candidate to face off against extreme-right leader Marine Le Pen.
Marine Le Pen, Emmanuel Macron and Francois Fillon all have chance of entering the Elysee Palace.
The pair does not want to split the anti-Le Pen vote.
What would an anti-EU, anti-US, pro-Russia France look like under Marine Le Pen?
Macron has inspired and energised a large section of French society with his centrist policies.
The election will be held across France in April and May 2017.
The leader of France's National Front is expected to come first in April polls.
Francois Fillon has appealed to traditional Catholic values while promising economic reform.
Europe must draw "red line" before polls this year, Obama's assistant attorney general warns.
Macron's party chief has said Russia is intervening in French elections just as it did in the United States.
The far-right politician used an anti-Semitic pun when responding to criticism by a Jewish actor.
The prosecutor has been investigating claims Fillon's wife was paid for work she didn't do.
Marine Le Pen would look to remove France from the single currency in six months if she is elected.
Both companies drew criticism during the US election campaign for failing to curb the spread of fake news.
The unusual romance of presidential favourite Emmanuel Macron and his wife Brigitte.
Global ratings agency says rising support for anti-EU agendas poses extreme risk to EU integration.
WikiLeaks' tweets come as many European countries step up their cyber defences ahead of elections.
The emergency status was first implemented after terrorist attacks on Paris in November 2015.
She says "playtime is over" and that foreigners should not expect free education for their children.
Fillon set to go head-to-head with the National Front's Marine Le Pen to be next French president.