The Blues suffered a 3-0 loss at the Emirates Stadium, only a week after going down at home to Liverpool.
Gunners beat the Blues 3-0 at the Emirates Stadium after goals from Sanchez, Walcott and Ozil.
Rashford has scored 3 goals in the Premier League for Manchester United this season.
Rooney, 30, was dropped for United's 4-1 win over Leicester City on 24 September.
Alexis Sanchez, Theo Walcott and Mesut Ozil were on the scoresheet for Arsenal against Chelsea.
Serge Gnabry rejected Arsenal contract extension to sign for Werder Bremen this summer.
Mario Pasalic is yet to make a single appearance for Chelsea after joining in 2014.
Manchester United scored four goals in the first half against Claudio Ranieri's side.
Two pre-season Premier League title contenders do battle at The Emirates Stadium.
James Milner notches a brace of penalties and Philippe Coutinho bags wonder strike in impressive rout.
Live coverage of the 3pm kick-offs in the Premier League including Spurs' trip to the north east.
The England skipper faces a crossroads in his career after being left on the bench against Leicester City.
Alexis Sanchez was not authorised to take the penalty against Hull City.
Arsenal have not won against Chelsea in five years in the league.
Wenger has won only once in his 15 appearances against Mourinho.
Leicester endure nightmare first-half collapse as hosts easily avoid third successive league defeat.
Schmeichel was a major reason behind Leicester City's title charge.
Mourinho had branded Wenger a 'speacialist in failure'.
Manchester City are unbeaten in their last eight games against Swansea.
Mourinho had criticised Luke Shaw for his error in Manchester United's 3-1 defeat to Watford.
Liverpool will play their second league match at Anfield against Hull City.
Giroud came through an intense training session on Friday to prove fitness ahead of Chelsea clash.
Aitor Karanka and Mauricio Pochettino took their coaching badges together at Madrid.
Dele Alli, Christian Eriksen, Eric Dier, Danny Rose and Tom Carroll all signed new contracts this month.
Arsene Wenger will come up against Antonio Conte for the first time when Arsenal take on Chelsea.
Real Madrid looking to return to winning ways at Estadio Gran Canaria.
Catalans visit the Asturian side following a 1-1 draw with Atletico Madrid.
Gray and Burnley have both accepted the four-match ban.
Former Barcelona star hopes to start in the London derby after scoring a brace against Leicester City.
The teenager has made a dramatic impact since his debut earlier this year.